[crazygringo]

I once went to a class once on bitters-making and learned that they can be made with water, alcohol, or oil to extract the flavors, and that all three versions will result in different flavors because they will extract different compounds in differening amounts.

(Also that some plants will have poisons that might be extracted in one method but not another, so you always want to research first.)

Obviously oil-based bitters aren't going to be compatible with cocktails because they won't mix in most cases.

But you can definitely make water-based bitters, if you want to avoid the flavors that alcohol extracts. But I think you'd then still add alcohol afterwards simply for preservation purposes, since you want a bottle of bitters to last for months/years and not need to bother with refrigeration.