I run Debian on my base machine and use Nix for all my user space tools. I think it’s the best of both worlds. I get nix for all my config management, but a normal stable distro underneath as a fallback.
Yep, also an underrated path! I had RHEL with nix briefly, so you got the support and stability of RHEL with the latest tools and packages from nixpkgs if you needed them.