[s1artibartfast]

Sure, there is a precautionary principle. Change nothing and you won't end up worse than before.

It depends on how risky you think the baseline factors are, and how risky you think the average new factor is. It also depends on how likely catastrophic risks are.

We know people don't drop dead from most things, so risk is generally at the fringe. Long lead times and low impact.

You then have to consider how many safe products you are missing out on to avoid the bad ones.

I think the the current paradigm is pretty reasonable. Screen for major known risks and then monitor and study

I think that breaks down when you compare Neolithic or pre-industrial man to now.