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by willy_k 739 days ago
> “Genetic predisposition for inactive aldehyde dehydrogenase enzyme and subsequent inefficient alcohol metabolism, may also play a role. In our patient, we suspect her recurrent antibiotics for UTI and dexlansoprazole use led to gut dysbiosis with potential contribution of genetics, resulting in auto-brewery syndrome.”

If the patient was genetically predisposed to have inactive ALDH, that would explain how they could reach such a high BAC without excess carbohydrate or exogenous alcohol consumption.