[taeric]

This is the second narrative I've seen recently where folks seem to think they have a strong argument against RTCs. Just, what?

Yes, there have been advancements in statistical tools. And we actively know some causal pathways. More, sometimes the expensive randomized trials are just not worth the standard ROI calculations...

But, to think that you have found some magic bullet against RTCs shows you don't really appreciate why they are so vital. And is usually a sign that you are reading the narrative of someone invested in an outcome.