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by yawpitch
742 days ago
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Likely precursors have been known in both bats and pangolins since virtually the start of the pandemic (see below) and are widely found in those populations to this day; the entire catalogue of possible precursor genomes in both wild bats and pangolins is (and likely will remain) extremely undersampled (to the degree we barely see any of the current picture of the wild viral load of these animals), so your apparent expectation of them being found in anything like the population of almost entirely domesticated populations of Arabian dromedaries (MERS) and entirely domesticated commercial cattle (current H5N1 spillover risk) is quite simply ludicrous. As it’s entirely possible the spillover mutation was either within a single, long-eaten, animal sample or occurred in a single human post-infection there’s no reason to assume the original lineage of SARS-CoV-2 itself would ever be captured in any wild animal population. I don’t even know how to speak to the bizarre (but possibly simply badly communicated on your part) assertion that human -> animal re-transmission events either should (or even could) result in a magic cessation of circulation in humans, as that’s just nonsensical. Post human SARS-CoV-2 lineage infections still persist in animal populations (mink, for example) and likely will continue to do so essentially forever… there’s literally nothing immaculate about this entire situation. https://www.nature.com/articles/s41591-020-0820-9 |
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