[jdefarge]

F1 is a successor of Megastore, even with relation to high write/read latencies. From bits leaked here and there by Google, one can safely assume they put highl value on cross datacenter consistency nowadays even if it means to hurt write ratios so much -- I recommend this video of Google IO 2011: http://www.youtube.com/watch?v=rgQm1KEIIuc (from minute 35:40 on). Megastore and F1 present abysmal latencies because they synchronously write to 3 data-centers at least before acknowledging the client side through Paxos or 2PC.

Only an idiot can assume that F1/Megastore is a drop-in replacement to MySQL (or Cassandra, jbellis!), but those guys invented BigTable, and battle tested it, long before writing the papers so they know where their priorities lie nowadays. On the other hand, I am highly curious about Spanner, the successor of BigTable, that powers F1.