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by derefr 749 days ago
I can’t speak for general solutions, but at least one portion of the addicted just have chronic pain; were prescribed extremely strong and addictive painkillers (as the only thing that would work!); and then got cut off from the medical system.

These people try and try to solve their debilitating chronic pain problem (which they still have, and likely will always have) through increasingly-desperate and illegal measures; and go through many harrowing things due almost solely of the illegality of acquiring these same drugs outside of medical channels: the difficulties of finding a source and potential for arrest; the income-eating expense (no insurance to cover costs, plus 10x risk markup); the heightened spike-dose addictiveness of street forms of these drugs, that leads to a quick fiending withdrawal and need to redose, leading in turn to loss of employment due to spending all your time on the street hunting for the next dose; and of course, the unpredictable dosing and potential for adulteration, leading into high potential for OD.

Most of this particular problem can (and in some trials, has!) been solved just by prescribing these people the drugs they need again. When you go from unpredictably doing random shots of freebase heroin/fentanyl/etc with a dirty needle alone in an alley, back to predictably being able to get precisely-dosed extended-release pills from a pharmacy and take them on a set schedule, a lot of “addict behaviors” for these chronic-pain “addicts” just evaporate.

1 comments

This is definitely a problem. Turns out once you start getting to the "going to destroy your liver / stomach" levels of NSAIDs and Tylenol, there really isn't anything other than opioids for pain management. Unfortunately the war on drugs and America's latent puritan streak means that since some people in some places use opioids to get high, then all uses of opioids should be avoided whenever possible, and when they are used, they should only be used grudgingly and with extreme skepticism of the person receiving them. Surely nothing will be better for the health of an individual than barely managing their condition, constantly forcing them to stop effective treatment to make sure they're not growing tolerant of the medication and treating them as only slightly more trustworthy than a criminal conman.

Sure, opioids are addictive, and you might find yourself in a situation where you're stuck on them for life and that's not great. And ultimately we have to ask "so what?" There are many conditions and medications that are lifelong and we don't treat the patients or their conditions the same way. Imagine telling a person taking SSRIs that they can't have a higher dosage because they're getting "tolerant" of the medication. Imagine telling a diabetes patient that you're not going to give them metformin or insulin because they might be on it for life. There are huge amounts of chronic conditions for which the ongoing treatments suck and have a lot of negative side effects, but living with the condition un-treated is worse than the negative side effects. Chronic pain (and the conditions causing that pain) seem to be the only category that we don't accept the possibility of long term negative consequences as the price of dealing with the chronic condition.

And the hell of it is, I agree with concerns about pill mills. My family that has had to deal with this has had to deal with pill mills too. And it's bad just having higher and higher doses thrown at you. I agree that treatment needs to include more than just escalating opioid doses. But those same family members that were stuck in a pill mill were there for years longer than they needed to be because finding a way out was nearly impossible. If you want to change pain management doctors, 99% of them will not prescribe you opioids on your first visit. But you likely have a contract with your current pain doctor that says you won't go to other doctors for pain medications, so you can't see a different doctor while getting pain management from your current doctor. Then even if you could get them to prescribe your medications, they almost all want to start you from zero again. Imagine you want to change heart doctors but before they will treat you they want you to stop all your heart medications for a few months so that they can "get a baseline" for your condition. That would be an insane thing to ask for any other chronic condition, and yet that's a common thing to be asked of pain patients all the time.

Overall as a society we're terrible at dealing with the concept of a chronic condition. We don't really grok the idea that some folks just won't ever "get better", and our entire system is set up to assume you will. The sad reality is some people are going to be in constant pain for their entire lives, and there's nothing we can do to stop that from being the case. Restricting these people from being able to safely access treatments to manage that pain because they might get addicted is misguided, cruel and missing the forest for the trees.

> Unfortunately the war on drugs and America's latent puritan streak means that since some people in some places use opioids to get high, then all uses of opioids should be avoided

Where were you the last 30 years? This comment sounds like you fell into a time warp from 1988.

No latent “American Puritanism” stopped Purdue.

https://en.wikipedia.org/wiki/Purdue_Pharma

True the recent shift is itself reactionary and with its own problems, but this one isn’t because of Nancy Reagan.

American Puritanism would also not explain having the highest rates of opioid prescriptions of peer GDP/capita nations in the world.

> there really isn't anything other than opioids for pain management.

1. Not true. 2. There are plenty of cases where opioids are ineffective just the same as NSAIDs/Tylenol.

> We don't really grok the idea that some folks just won't ever "get better"

Yes, we do. If your oncologist doesn’t prescribe you appropriate analgesia or refer you to a palliative care practitioner then find a new one.

> and our entire system is set up to assume you will.

This is one of the more unusual and unhinged takes I’ve ever heard in this era of diabetes, A-fib and COPD medications advertised on TV and every street corner (none of which are curative).

The vast majority of non surgical medicine is about chronic disease management. Medical cures are the exception.

> The sad reality is some people are going to be in constant pain for their entire lives

The sad reality is that the medical industry was complicit in causing unnecessary suffering due to the legitimized medicalized misuse of opioids and this is the aftermath.

>True the recent shift is itself reactionary and with its own problems, but this one isn’t because of Nancy Reagan. >American Puritanism would also not explain having the highest rates of opioid prescriptions of peer GDP/capita nations in the world.

I would argue that a non-puritan society would look at concerning rates of recreational opioid use and abuse and try to solve the underlying problems that are driving people into that instead of treating them as criminals for their choice of dug to abuse and putting policies and laws in place that make legal medical access to opioids increasingly ridiculously convoluted and scaring doctors away from prescribing them. That puritan streak is what underlies the societal revulsion to "drug addicts" and reacts with an attitude of "cut them off". It's what makes society view addiction as a moral failing on the addicts part, and it contributes to a lack of resources and help for people looking to escape that addiction. Sure if you're extra wealthy you could check yourself into a hollywood rehab center, but for the rest of us lowly schmucks, your average local rehab centers are cold places that will do the bare minimum to make sure you don't die, and then throw you back out into the world with no more resources or support than you had before, to face the same problems that drove you to your addictions again.

Or one could also look at the media and public reaction to Perdue's support for the concept of "pseudo-addiction". While the media and public mock this as laughable at best and dangerous overpromotion of drugs at worst, there's nothing unreasonable about the concept at all. The idea is really simple, that perhaps some people who exhibit addiction behaviors like "taking more pain medications than prescribed", "focus on when they can take their next dose", "moaning or vocalizing in pain", "demanding specific medications", "seeking to keep a extra supply" might not be addicts but might actually be - you know - in pain (due to an inadequate treatment regimen). And that seems obvious right? Like if you had someone who was being given say, 200 mg of ibuprofen every 6 hours for a broken leg, you might expect them to do some or all of those things right? I know I certainly would. And yet, switch from ibuprofen to opioids and all of a sudden people think this is ridiculous.

> 1. Not true

Fair enough, I should have say there isn't "much", and the things there are can have plenty of their own bad side effects even if they aren't "addictive". Steroids would be an option. Long term use of which can among other things raise your blood sugar contributing to diabetes, increase your chances of getting infections, increase osteoporosis, increase bruising and slow healing in general. Anti-epileptics can help if your pain is specifically nerve pain, and anti-depressants can help in some cases too, though again with their own non-insubstantial risks.

> Yes, we do. If your oncologist doesn’t prescribe you appropriate analgesia or refer you to a palliative care practitioner then find a new one.

Anyone with a chronic and disabling medical condition could probably give you a book worth of experiences where doctors, co-workers, family and friends became increasingly exasperated or frustrated by the fact that they do not in fact get better and continue to require accommodations. I'd also point out there are other conditions that cause high levels of chronic pain that aren't cancer and aren't terminal. Getting palliative care (or even someone to understand that you need palliative care that isn't also end of life care) in those circumstances is an uphill battle to say the least.

> The vast majority of non surgical medicine is about chronic disease management. Medical cures are the exception.

And one need only participate in any discussion about modern medicine and care to see how much people are against the idea of lifetime medications and treatment. See also recent sturm und drang over Wegovy for treating obesity. Perhaps a better way of phrasing it would be "if you don't have a specific set of well recognized 'incurable' conditions, our society and medical system is set up to assume you will get better". It's especially bad if you have slow and largely "invisible" disabilities. My family member that had to deal with the pill mill doctor was in that situation because they were being passed from doctor to doctor to doctor all of them wanting something that some other could treat to "get better" first before they wanted to do anything. And the pill mill doctor was no different, kept throwing more pills at them until "your condition improves and then we can look at other options". It took us nearly 6 years to finally put together an actual team of doctors that were interested in coordinating and understood that this wasn't ever going to go away and that treatment was going to mean sometimes one thing or another would get worse while the other aspect was treated.

>The sad reality is that the medical industry was complicit in causing unnecessary suffering due to the legitimized medicalized misuse of opioids and this is the aftermath.

And how many thousands or millions of others will be put through more unnecessary suffering in our reactionary spasms of guilt in this aftermath? How many lives will we lose to suicide because the alternative is facing a life of poorly managed pain and being treated like a criminal for trying to get treatment? How many people will be drive to ever increasingly desperate measures to obtain illegal pain medications as their options for legal paths are closed or made more and more unworkable? How many people will we leave in pain because they "might get addicted" as if being addicted to a tolerated but effective medication is the worse then being in disabling levels of pain? How many innocent people will we allow to suffer, because we are unable or unwilling to punish only the guilty?

You completely extinguish the patient (and population) safety issue over some mealy mouthed allusion to American Puritanism while completely just ignoring unaddressed the main counter that most other industrialized nations never matched the high level of opioid uses or its skyrocketing growth in the 90s.

It reminds me of this https://www.sciencedirect.com/science/article/pii/S009130572...

which in addition to hawking a number of questionable co-opted concepts is literally stating the equivalent of “risk of death from automobile ejection is now super low these days therefore seatbelts must not be necessary”, which is ballsy to put out there (or not so much if you’re retired).

This and your wall also just completely ignores the diversion issue. Ibuprofen may have harms but no one is selling it for $20 a pill or more to people that end up dead. The methods to avoid it at the end of the chain are laughably terrible, annoying or even harmful to legitimate users and not an impediment at all to diverters.

This is a complex medico-ethical-legal and public health issue, "hurr durr, those nasty right wing puritans" is uselessly reductionist.