[throwaway2037]

It must be minute quantities -- if any at all. In developing countries in Asia, it is pretty common to eat the whole mango without peeling it first. (Before anyone responds to this comment: Yes, I have personally seen this eating style in many different countries.) Usually, you just cut two pieces: top and bottom, then discard the seed. It also makes it easier to hold the cut fruit with your hands without getting too sticky / dirty.

However, when picking mangoes, you need to be careful about the sap that comes from the broken stem. That will cause a rash, and also disfigure the fruit's skin (which hurts market value). You can Google about it.

[engine_y]

I have done it myself multiple times. Whether you can eat the skin depends on the mango strain. Some are really thin.

[NoRagrets]

The kitchen tradition is to soak them in hot water for 3-4 hours. All imported mangoes that come into the US also get the same hot water treatment. They say it’s for fruit flies but back home it was suggested to reduce rashes.

[..]Hot Water Treatment Requirements According to USDA APHIS requirements, for rounded varieties (Tommy Atkins, Kent, Haden, Keitt), the treatment for fruit flies requires heating in 115ºF (46.1ºC) water for 75 to 110 minutes, depending on the weight of the mango.[..]

https://www.mango.org/wp-content/uploads/2017/10/Alternative...

In Ayurveda, ripe and unripe mangoes.. mango bark, leaves, roots, seed and flowers are all considered to have medicinal qualities.