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by modeless 766 days ago
Oral immunotherapy is indeed dangerous. Eosinophilic esophagitis is real. Anaphylaxis is common. It's a long, tedious road, with daily dosing for years, and in many people the treatment ends in failure rendering the effort wasted.

Although many do achieve remission, there is no guarantee that the allergy is gone for good. The immunity obtained by immunotherapy is not necessarily the same as natural immunity. It may not be complete and it may not be long lasting. The immune system has a long, long memory and we do not have any reliable tests to determine if anyone's immunity is permanent. For that reason allergists recommend continuing dosing indefinitely to maintain immunity, and continuing to carry an epi-pen. For the rest of your life. You will get sick of peanut butter.

All that said, we are doing sublingual immunotherapy for our son. But I am hoping that within his lifetime new treatments are developed that will free him from allergies completely.

Precise control of the immune system would be the holy grail of medicine IMO. Dysfunctions of the immune system are at the root of so many diseases, not just allergies. If the immune system could be easily trained to ignore or attack arbitrary targets at will it could likely cure almost any infection or cancer. And I bet it could be useful in treating the diseases of aging as well.