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by mrtesthah 759 days ago
Zbiotics gives you genetically modified probiotic bacteria that secrete ALDH into your gut.
1 comments

I'm not sure how that's helpful. It looks like ALDH is responsible for breaking down acetaldehyde. However, the pathway for ethanol to become acetaldehyde happens primarily in the liver with ADH. So while this may flood your stomach with ALDH, that's mainly only useful in the blood stream after alcohol is metabolized right?

Is the theory here that because the digestive tracks is a large organs filled with blood the resulting ALDH would interact?

My next question is do these, and how many, probiotic bacteria survive the acid wash of the stomach?

Are there studies around this?

I think most of the ALDH from the stomach/LI would end up in the liver though.