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by signal_space
768 days ago
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Is alphafold doing model generation or is it just reducing a massive state space? The current computational and systems biochemistry approaches struggle to model large biomolecules and their interactions due to the large degrees of freedom of the models. I think it is reasonable to rely on statistical methods to lead researchers down paths that have a high likelihood of being correct versus brute forcing the chemical kinetics. After all chemistry is inherently stochastic… |
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