I’ve been using it for many years, I think it’s one of the oldest alternative mouse driver for Mac. Highly recommended to those who want to avoid the bloated (and now AI powered, for whatever it means) Logitech software.
AFAIK, the AI thing is just shortcut/macro button(s) to activate ChatGPT? It's not like they put AI in charge of determining where you meant to click, or anything goofy like that.
Some mice will have buttons that toggle lighting or tracking speed, I have a feeling these are the kinds of buttons that might not work with the app. Because they are just local buttons, they don't get sent to the OS.
It’s varied a lot by version of the software, and by iterations of the mouse models with such functionality. I recall at least one Logitech mouse where the buttons couldn’t ever be reprogrammed; at least one other where it was unsupported before a SteerMouse update; and others where they were supported like any other mouse button on arrival.
Edit to add that IME most have fallen into the last category for a several years now.
It does on my MX Vertical. It also lets you set different actions per app. I've used that to bind the forward and backward buttons to do the right thing in most apps I touch so I have a universal shortcut for that navigation.