If you like Caddy for it's ACME capabilities, then you might enjoy Traefik as well. It supports HTTP, TLS ALPN and DNS challenges and can be configured in one line as well.
I already use it as a web server and reverse proxy so it's a better match. I've tried traefik in the past and it wasn't as simple as caddy to configure. Caddy has some well thought out magic (like creating a sane modern php config with just one line).