I thought Splenda has almost nonexistent calorie and I am not sure what makes it different from aspartame functionally. Any reputable research on the direct damages caused by Splenda?
The study above references 4 different studies that indicate that artificial sweeteners can affect glucose tolerance through changes in the microbiota composition:
The article also references 4 studies that indicate that artificial sweeteners have side effects in terms of obesity, cardiovascular disease, and mortality.
What about dosage? I couldn't find a succinct summary. Can you point out the part indicating how much they experimented with? How many grams of Splendar per day would indicate danger?
The study above references 4 different studies that indicate that artificial sweeteners can affect glucose tolerance through changes in the microbiota composition:
- https://www.nature.com/articles/nature13793
(free PDF here: https://d1wqtxts1xzle7.cloudfront.net/44081512/Artificial_Sw... )
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363527/
- https://www.cell.com/cell/fulltext/S0092-8674(22)00919-9
- https://www.cell.com/cell/fulltext/S0092-8674(22)00994-1
The article also references 4 studies that indicate that artificial sweeteners have side effects in terms of obesity, cardiovascular disease, and mortality.
- https://www.bmj.com/content/378/bmj-2022-071204
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538252/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9506029/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8946744/