[notdonspaulding]

GBM median survival for humans (according to the article) is 15 months.

If the effect is linear, the boost to survival time in humans would be an additional 19 months. With the death sentence of GBM hanging over your future, an additional year-and-a-half is huge.

[SoftTalker]

It is and it isn't. A year and a half would go by so quickly. But if it were a high-quality year and a half and not spent in a hospital ward, I guess it's better than the alternative.

[magicalhippo]

It's highly non-linear, as you allude to.

For a mother with a young child, getting another 1.5 years can be the difference between the child not knowing their mother and having some memory of her.

For someone with no or adult children, it can be a lot less significant. My dad passed away from cancer when I was 30 and while I certainly would have taken an extra year with him, it wouldn't have changed much.

[CalRobert]

Nothing like a deadline to make the most of 18 months. I have a 4 and 6 year old and if I were in this situation I'd cherish the hell out of that time. And hope for further improvements in treatment (and a stroke of luck) in the meantime.

[notdonspaulding]

It is and it is. My dad died of a GBM in 2022, 17 months after his diagnosis. If he had had another 19 months, I'd have made him breakfast this morning.

I find it much easier to sympathize with people's desire for additional time with terminally-ill loved ones now.

[afavour]

How about we could let people make that decision for themselves?

[SoftTalker]

I said nothing about making the decision for anyone else.

[agumonkey]

I'm in the camp of having 18months of non painful survival being a massive change, because it buys you time to wait for another therapy later.

[panosfilianos]

You could say the same for 20 years, in the grand scheme of things.