[throwaway11460]

No technical reason, but you won't be able to run a compiled binary due to policy. You need to use an interpreter.

[cyberpunk]

I wonder if qemu with cpu=host counts...

[greenavocado]

Maybe run a VM inside Safari via QEMU and WASM that boots a Linux desktop environment

[lxgr]

WASM is indeed one possible workaround. That's how a-Shell [1] manages to include a C compiler and run resulting programs at (I believe) better-than-interpreted speeds.

[1] https://holzschu.github.io/a-Shell_iOS/