[magicalist]

Megaupload is a good cautionary tale. IP 'holders' have enough power to do bad things if they can cast you as a bad actor, so far better to have some kind of take down support that works for the country you operate in.

Manual processing of requests is probably fine for many launching apps (unless there is the possibility of automated content creation on the part of your users), which also lets you be really careful with complying with applicable laws while (crucially) maintaining the rights of your users.

But, yes, if you're in the US and want to maintain safe harbor protections, you will have to handle any takedown requests you receive.