> I mean come up with a pill that changes your eating habits and doesn't just repress them. Don't think anyone's got close to that yet.
So GLP1 gene therapy (if it ever gets here) might be the most reasonable way to achieve this, and might be the safest we've ever seen so far outside of maybe brain control.
> In the meantime overweight people are going to take what they can get.
100%. And AFAIK GLP1s are some of the safest we've seen so far, and much more effective than "eat less and move more" (as true as that may be).
Tobacco did that (imagine going for nicotine patches instead of smoking), meth did that, a lot of things do that. It all comes down to the side effects and whether it's worth having the drug around.
Up until now we say "no, fuck it" after a few decades of having the thing widely available. My point is wether we should shortcut the cycle and so no _before_ doing the society wide trial and having to fight for decades to have it stop.
> In the meantime overweight people are going to take what they can
Tobacco and meth happen to be some of the most highly addictive drugs that exist, that also have the side effect of weight loss.
I don't think I've seen anybody tweaking out for a fix of ozempic, though please feel free to inform me if addiction is an actual side effect that I've not heard of.
Withdrawal for tobacco is basically mild discomfort. It can't be in the same class as drugs that cause seizures, profuse sweating, and death upon immediate cessation.
Depends what you mean by mild. For me, going cold turkey from nicotine was migraines, severe anxiety, irritability, and fatigue. Not life threatening, but I was unable to function. That said, tapering off with a controlled time-release dosage (patches) was sufficient to reduce it to actual mild discomfort for me.
Ozempic has started to be in wider use very recently, and we know it has a side effects of restraining dopamine release.
My point is we still know very little about long term effects, and in particular about what happens when the brain's reward centers are affected at scale (for a diversity of people) + for years.
Yet we're already going down the path of the "miracle drug" [0] and that freaks me out.
So GLP1 gene therapy (if it ever gets here) might be the most reasonable way to achieve this, and might be the safest we've ever seen so far outside of maybe brain control.
> In the meantime overweight people are going to take what they can get.
100%. And AFAIK GLP1s are some of the safest we've seen so far, and much more effective than "eat less and move more" (as true as that may be).