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by hungrigekatze 786 days ago
There were 5882 cases of CJD between 2007 and 2020 in the United States (not specific to CWD though). Nonetheless, when I learned of that tally a few weeks ago I didn't expect the tally to be so high. Public health messaging had conveyed to me that CJD was an extremely rare occurrence in the US.

A larger-than-expected percentage of people Dxed with CJD are elderly (mid-70s to mid-80s) women which leads me to wonder if medical equipment was used when delivering babies exposed many women? I wonder if their children (who were being delivered) were also infected? In deer the mother-offspring infection route's quite well studied, but I'm not well informed about the human offspring route.

--- Full paper here (not free): https://jamanetwork.com/journals/jamaneurology/article-abstr...

The article in JAMA, above, has been summarized on this page: https://www.neurologyadvisor.com/topics/neurodegenerative-di... I'll paste the summary text below:

The incidence of Creutzfeldt-Jakob disease (CJD) has risen considerably from 2007 to 2020, particularly among older women, according to a research letter published in JAMA Neurology.

The progressive, universally fatal prion disease CJD has been stable in the United States (US) between 1979 to 2006. The most common subtype of CJD, sporadic CJD, tends to affect older individuals. As the global population ages, the epidemiology of CJD may be evolving.

To evaluate recent trends in CJD in the US, the researchers sourced data for this cross-sectional study from the Wide-Ranging Online Data for Epidemiologic Research multiple cause of death database. Death certificates between 2007 and 2020 for CJD were assessed for volume and decedent demographics.

The incidence of CJD increased consistently between 2007 and 2020, in which there were 5882 total cases and 51.2% occurred among women.

[article continues on the Neurology Advisor page]