[nickburns]

my comment is limited to "acute, traumatic soft-tissue injury", the scope of which excludes viral infection, allergic reaction, and strict joint injury.

[naasking]

> my comment is limited to "acute, traumatic soft-tissue injury", the scope of which excludes viral infection, allergic reaction, and strict joint injury.

The point is that evolved responses don't always properly account for nuance or proportion. If inflammation evolved for large traumatic injury, it may still be triggered for limited soft tissue injuries but then the response could be disproportionate.

[lrasinen]

Those examples were more about the body's tendency to overdo its response.

(But aren't joint injuries usually soft-tissue as well? It's the ligaments that get the short shaft.)