I got made fun of for being a Y-inverted person, but I had my revenge when none of my non inverted friends could reliably control the bucket on a front-loader I had rented. Neener neener.
The first game I played with mouse support in the 90s, I believe, was Flight Simulator 3.0, and I think by default (?) it was set up for inverted mouse (or was MS-DOS Star Wars: TIE Fighter, can't remember).
Since then, when I started playing other FPS games with mouse support (like Quake and similar), this mode prevailed.
However, the biggest challenge came years later with FPS games for smartphones - retraining my mind to play with non-inverted orientation. Quite an adventure!