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The end of Microsoft in Europe will be its poor security.

These massive integrated bundles of fluffy convenience are cybersecurity death-traps that leak personal data like a rusty bucket. Firms are rightly getting very nervous about massive fines, and blaming MS is not a get-out. With Microsoft unable to reign-in the complexity of their own products they'll lose market share to smaller, more specialised but more secure systems.

Ironically the path to better security for Microsoft would be to partition/split their own products as the anti-monopolists would have them do.