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by InSteady 814 days ago
>The ketogenic diet has been proven to be effective for treatment-resistant epileptic seizures by reducing the excitability of neurons in the brain

>There is increasing evidence that psychiatric diseases such as schizophrenia and bipolar disorder stem from metabolic deficits in the brain, which affect the excitability of neurons, Sethi said. The researchers hypothesize that just as a ketogenic diet improves the rest of the body’s metabolism, it also improves the brain’s metabolism.

I wouldn't be so quick to look for the most reductive/simple answer. Drastic dietary changes can have a huge impact on the microbiome, which can in turn lead to substantial changes in all kind of signaling between the gut and brain (in terms of hormones, immune molecules, neurotransmitter precursors, and much more). There may also be implications for cellular metabolism.

As the quote above touches upon, many mental health disorders may have a component of disruptions to metabolism and energy balancing on the cellular level. Possibly including ADHD, autism, treatment resistant depression, and OCD, in addition to schizophrenia and treatment resistant epilepsy.

2 comments

I agree, I do also wonder what the role of routine and following through on commitments is. Getting things done alone can make people feel better and more confident.
Yeah, I think the connection between mental illnesses and physical health is a seriously under researched topic. At least, it's not something that's in popular science anyway.