[wizzwizz4]

This article buries the lede, but boy is that lede fascinating.

> Estrogen receptors are known to bind to certain regions of the genome when a cell is stimulated by estrogen. The researchers found that these estrogen-binding sites were frequently next to the zones where the early DNA breaks took place.

Estrogens are important for other things, so (what's effectively) menopause would be a rather impractical preventative measure for most people – but knowledge is still power. I'll have to read the paper sometime.

https://doi.org/10.1038/s41586-023-06057-w