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> In one CPU you have cores of different sizes and different speeds

In this case yeah, but not all of them. I believe AMD still makes some desktop CPUs without those compromises, but they're still slowly starting to put out CPUs like the 7950X3D that have crippled cache on certain cores (7950X does not, 7800X3D does not).

Of course big.LITTLE has been a thing in ARM for decades, including ASi. But I believe Intel started doing E-cores because they were starting to run into space and thermal constraints, and now AMD is exploring heterogeneous architectures as well. I hope they won't repeat the same mistakes.