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by inciampati
828 days ago
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What's more, this isn't history. Code from the Celera assembler lives on in a lineage of assembly methods (Canu, HiCanu, Verkko) which have ultimately _completely automated the process of complete genome assembly_
https://doi.org/10.1038/s41587-023-01662-6. The fact that this assembly approach remained relevant until practical resolution of the assembly problem is a testament to its solid theoretical foundation (the string graph) which relates read length, error rate, and information theoretic limits of genome assembly https://doi.org/10.1093/bioinformatics/bti1114. |
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