[nyrulez]

Do you know the amount she was consuming and the brand? Total Dosage, dilution and the per unit strength of the ACV brand can really matter, like anything else we might consume.

The paper does do a good job of describing this pretty important detail: "Groups 1, 2 and 3 consumed 5, 10 and 15 mL, respectively, of ACV (containing 5% of acetic acid) diluted in 250 mL of water daily".

I can almost guarantee if that amount went up to 30-50ML and without any kind of dilution, effects can be pretty adverse.

I've been consuming it by diluting a tablespoon of ACV heavily with some warm water that I can barely taste it. It's really helped fix my acid reflux while all the prescription drugs from my PCP didn't seem to do anything.

[amluto]

The placebo was dilute lactic acid of similar pH. So one might imagine that the acidity didn’t cause the effect and try neutralizing the vinegar. Add, for example, calcium carbonate (cheap and safe) to convert most of the acetic acid to calcium acetate, leaving a neutral solution with extra calcium. Whatever magic other compounds in apple cider vinegar are beneficial seem likely to survive that process intact. The net result would be similar to drinking the vinegar and eating an antacid, minus the tooth damage.