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by ravenstine 838 days ago
Glycemic index is only sort of useful for people who actually have diabetes, where blood sugar dysregulation makes insulin regulation equally as precarious. For anyone who doesn't have diabetes, GI doesn't really mean anything other than that their insulin may or may not spike in a short period of time related to a food. Glucose spiking, hence insulin spiking, is not something you want, but this also doesn't mean that something with a lower GI score is better for you and doesn't cause you to release as much insulin. Whether it's table sugar or whole grain pasta, they'll become glucose that the body will use or store in one way or another. Fasting glucose will still remain higher.

> Devices like this will make other people fearful of high glucose and think they're getting diabetes.

Elevated glucose is exactly what causes type 2 diabetes. Take away the glucose supply, and you don't have elevated insulin. Fear of glucose that is too high too often is entirely justified and is not something that should be going on if people can avoid it. Sugar molecules are damaging to cells and are related to other things like cardiovascular calcification.

> If we look at the Blue Zone, many people eat mostly carb.

So-called "Blue Zones" are not science. They are anecdotal, cherry-picked, uncontrolled, and can't be tested. Also, some of those zones, such as Okinawa, are mythical. Okinawans historically have eaten a lot of pork, and still eat a ton of pork. They also used to not keep much in the term of birth records, so there was really no way to know how old any of those people were back when they were studied.

> So carb/high GI food definitely doesn't cause diabetes.

Propose a model of type 2 diabetes that doesn't involve dysregulation of blood glucose and come back to us.

2 comments

> Elevated glucose is exactly what causes type 2 diabetes. Take away the glucose supply, and you don't have elevated insulin. Fear of glucose that is too high too often is entirely justified and is not something that should be going on if people can avoid it. Sugar molecules are damaging to cells and are related to other things like cardiovascular calcification.

No, it doesn't: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6602127/

Reread that article. It has literally nothing to do with cause and effect. The study finds an association between intramyocellular lipids and insulin resistance, and has absolutely nothing to say about whether diabetes is caused solely by glucose dysregulation or something else.
Every response you have don't relate to my comment! and I believe you have incorrect info in your responses as well.
Surely you have a good example of what I am incorrect about instead of merely saying I am wrong?
Your comments aren't the responses to my comments. Let's take an example, my comment is neither proposing a model for T2D nor saying CGM is part of any model.

You said Okinawa people eat a ton of pork, please compare with something.

You said they don't have birth record accuracy which is not totally true. In many asian culture, they use Zodiac and similar methods to keep track of age, the exact date may be off, but the year cannot be off because if it's off, that's 12 year difference. I cannot be a dragon and claim myself to be 84 when I am only 72 because all of my friends around know how old I am around.

When 1 or 2 persons say it, it may be mythical. But when most of population say it, there must be some truth. And it's also up to you how you believe it.