[pjc50]

You absolutely can tell the CPU what to cache, and also what not to cache (such as PCIe memory-mapped registers), it's just that that's privileged instructions which no sensible multitasking operating system will let you have access to. Because it would have to be reset on every task switch.

[bombcar]

I’m still disappointed that you can’t boot a modern processor with its 8MB of L2 cache and run Windows 95 entirely in cache. Stupid requirements to have a backing store.

[pclmulqdq]

I think if you flip the right MSRs, you can actually run in this mode on Intel. BIOSes used to do DDR3 calibration in this mode, and needed to run a core DRAM-less to do it.

AMD Zen platforms have always put that functionality (ironically) in the secret platform security coprocessor.