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by lettergram 843 days ago
I’ve been on Dupixent and have a large number of allergies.

100% helped eczema. I used to have it to the point all my fingers were split in 5-8 places and I’d rate the pain scale at 8-9/10 (10 being arm cut off). I used to get blisters under the skin that’d combine and basically just peal off the skin - https://www.mayoclinic.org/diseases-conditions/dyshidrosis/s...

Anyway, Dupixent made it entirely go away. I also found my allergies did improve (suddenly wasn’t allergic to dogs). That said, it did have a side effect of severely drying out my eyes and I’ll get weird rashes on my face periodically and it requires injections 2x per month. That said, I can use my hands now, frankly I can think too. Pain is gone, and idc about the symptoms.

2 comments

I had the exact same experience.

I'm on Dupixent indefinitely for eczema, which it cures 100%. As a side effect, it 100% cured my seasonal hay fever and reduced many of my food allergies to a level, where I can just eat the food and ignore the very slight allergic reaction that remains.

For me, the entire field of monoclonal antibody therapy is pure magic. Absolutely amazing how well it works, a true silver bullet (with home injections twice a month and eye drops for the dry eyes).

I get dyshidrotic eczema on my hands, have for decades, and had no idea dupixent could help that. It doesn’t cause me pain though; the blisters and peeling skin are certainly annoying, but the side effects sound like the same level of annoying.
UV light therapy may be an option for that. It's even possible to self-administer with a 365nm UV flashlight, which I have done successfully. I'll stop short of recommending anyone else actually do that themselves, but I will definitely do it again if my symptoms return.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7497185/