[mutagen]

They do.

For instance, Logic Pro

https://support.apple.com/guide/logicpro/tuning-project-sett...

Many DAWs stay out of tunings and leave that for the individual virtual instruments. There's a standard for that named Scala (yes, also a language).

https://www.huygens-fokker.org/scala/

[resters]

Thank you. I want to set it up for various temperaments and play some piano music through it live in each temperament (via my midi piano)