[1letterunixname]

It's the most widely-abused performance enhancing drug, but each person will need to assess the tradeoffs, long-term implications, and unknowns:

+ Productivity

+ Focus

+ Clarity

+ Symptomatic cure for migraines

~+ Probable neuroprotectiveness

~ Mild anorectic

~- Unclear GERD risks

~- Weak anticholinergic - probably not tardive dyskinesia or dementia, but the long-term effects are unclear

- Increased heart rate and blood pressure

- Diuretic

- Higher cortisol levels

- Dependency

- Tolerance

- Caffeine withdrawal headaches

- Slow caffeine metabolization (CYP1A2 rs762551 CC/CA) vs. fast (AA)

[aworks]

I wasn't aware of the migraine cure.

When I had headaches, my neurologist told me to cut out alcohol, binge TV watch and caffeine. That helped but did not cure me.

Then during the pandemic I started the enjoyable daily habit of drinking sparkling HopTea (some caffeine, no alcohol). It's definitely a diuretic but I can't say about other symptoms