[tudorw]

Did you look at using PHATE for dimension reduction?

[enjalot]

I hadn't seen it, looking at the API it seems like it could be pretty straightforward to drop it in and see how the projections look.

[tudorw]

I'd be really interested to see if that works out. There's some interesting comparisons here; https://www.nature.com/articles/s42003-022-03628-x