[oortoo]

Some substances at least make people more social or more engaged and empathetic. Any drug that makes someone stare at their lap and not respond to outside stimulus is probably bad for social settings.

I don't do drugs (anymore) but I enjoy hanging out with people who can use drugs and be social.

[teaearlgraycold]

Ketamine?

[jjulius]

Are you asking about this with regards to it being used socially? Depends on the environment and the people obviously, but in the places I'm exposed to it (underground electronic music events) I know many people who are still able to function socially while using it. Yes they're high, but they don't consume enough to fall into a k-hole.