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by BenFranklin100
862 days ago
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‘Utterly wrong’ is a harsh conclusion. You may want a touch of humility yourself. Amyloid plaques are the defining feature of AD and assuredly provide vital clues about the biomolecular processes driving AD across the brain. There is renewed interest in the what causative role amyloid plays [1]. Whether plaques are causative or a byproduct is an open question, especially when we consider the heterogeneity in neurodegenerative diseases. AD itself probably is an umbrella term capturing several subtypes (such as CAA). Whatever role amyloid plays, the OP is correct: correlates open interesting research avenues and this is an interesting paper if for no other reason we have few predictors of who will develop AD. [1] https://www.nature.com/articles/s41392-023-01484-7 |
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