[folli]

I guess that depends on your exact ecological niche within bioinformatics.

I got my start at a NGS facility, so handling FASTQ was closer to 80% of my time, so any speedups would have been greatly appreciated.

[MillironX]

> I guess that depends on your exact ecological niche within bioinformatics.

Agreed. I know people in my department who just ran Galaxy pipelines and R scripts to make pretty plots. I was on the other side of the spectrum and needed fast parsers, so the SAM and VCF specifications were my bible.