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by evandijk70 870 days ago
AFAIK there is currently know way to reliably tell from DNA sequencing data whether a prostate cancer will become dangerous. That may change, but I suspect there may be some inherent stochasticity in the transition of a cancer from benign to dangerous that will make a perfect classification possible. I would guess some form of monitoring may be required for all the currently non-dangerous cancers.
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Yes, I had a glimpse at current research, it’s being worked on, but it’s not yet there. Also sequencing is still too expensive for more general application.
Genotyping assays for single nucleotide polymorphisms (SNPs) are relatively cheaper (I may not be up to date). In the space of 'polygenic risk score' of these genomice variants it is still a bit of debate how useful it is for screening.