[100pctremote]

5-pin DIN is still the more stable option today and doesn't introduce any noise, unlike USB which carries power.

[jojobas]

Noise in midi? Seriously?

[uxp100]

Yeah, I’ve got devices where there is a hum on their output while using usb-midi. 5 pin midi should not have such issues (but if done badly could)

[adw]

Yep. It's not noise on the MIDI signal, obviously, it's crosstalk induced by USB circuitry. It gets worse when bus power is involved; USB-powered instruments are notorious for it.

[jacquesm]

MIDI is galvanically isolated, USB is galvanically connected so you can have groundloops if you use USB but not if you use MIDI.