[bradrn]

I honestly don’t see the point of using LaTeX if you’re generating HTML. The great strength of LaTeX, in my view, is the precise control it provides over typography and formatting. As such, it works best with an output format which can faithfully render these documents — such as PDF. For an output format like HTML, which encourages reflowability over faithful rendering, I’d much prefer to use an ‘easier’ document format like Markdown or reStructuredText.

[golol]

Exactly, there is a triangle of tradeoffs here: prettyness vs easyness vs responsiveness. You can only have 2 of them. pretty and easy is Latex. The reason people call CSS a nightmare is because responsiveness fundamentally makes it much more difficult to make a document pretty. So HTML+CSS gives you pretty + responsive or easy + responsive. That's not the same functionality as a pdf for a fixed scientific document.