David Sinclair is a social media influencer more than anything else. His insistence on life extension through lifestyle alone is telling, because it's so easy to sell to the general public. Except this doesn't work and can't work — if an organism has a goal to destroy itself, which it does as part of its aging program, it WILL destroy itself, no matter how much you change its environment. You need to overwrite that internal goal state to truly cure aging which can't be done through any manner of lifestyle interventions.
Effective advocacy begins with letting go of the assumption that everyone already knows about the things you know about. I'm sure this person is well known within the bioscience community, but this is the first time I'd heard of him or his model.
> This technique also extended the lifespan of mice with a premature aging condition by about 40%.
Why is it always like this? Even "in mice" I think they always start with an animal that has been genetically modified to age faster or show some trait of aging and then cure that, as opposed to taking a normal healthy mouse and extending its age by 40%, no?