Any program that interacts with the OS - interacting with files, allocating memory, etc - will have to make system calls. Whether it's in C, Rust, Zig, Haskell, APL or Prolog.
I want to note that this is also true for “managed” languages like Java and Python.
However, because these languages have a far heavier runtime than the “systems” languages, it is usually possible to trace them at the runtime level rather than the syscall level, and doing that will typically give a better experience.
However, because these languages have a far heavier runtime than the “systems” languages, it is usually possible to trace them at the runtime level rather than the syscall level, and doing that will typically give a better experience.