Depending on the size of the keyboard and on the size of your hands, using the left modifier for that shortcut might need two hands instead of just one; it's very convenient to be able to quickly lock the desktop with only one hand.
I just tested and,on a full size model m, I can still stretch 2.5 inches after reaching the left+win from my pinkie and l with my thumb. And I have average hand span for a man.