[kortex]

Ok, so make sure you get enough dietary manganese?

RDA for Mn is 1.8-2.3 mg/day. Tolerable upper limit is 11mg/day. Mn ions are highly conserved in the body and mostly cycle through redox states and various complexes.

That's actually a pretty narrow therapeutic window, again because it's a trace mineral and biology has evolved to recycle it very efficiently.

[Podgajski]

Yeah, that’s what I thought until I had my hair and serum levels of manganese tested. Which were both low. And taking manganese cured not only my chronic fatigue, but my insomnia and anxiety as well.

Also, there’s a study at Stamford going on right now, looking at manganese levels and illness and they’re finding that these ranges are old and arbitrary.

And that tolerable upper limit is a joke since I had to take 30 mg a day.

Just do a little research and find out where they got those limits and ranges from.

But, regardless, it proves my point, that exercise depletes manganese and that could cause disease in people who don’t have sufficient manganese. So just telling everyone to work out and you’ll live longer is a false statement.

Adding

https://www.efsa.europa.eu/en/efsajournal/pub/3419

There are no reliable and validated biomarkers of manganese intake or status and data on manganese intakes versus health outcomes are not available for DRVs for manganese. As there is insufficient evidence available to derive an average requirement or a population reference intake, an Adequate Intake (AI) is proposed.