AFAIK, this is typical of USB controller chips, which generally have about 20-30 I/O pins, but I’m sure there are outliers.
The AGC seems to have four 16-bit input registers, and five 16-bit output registers[2], for a total of 144 I/O pins total.
[1] https://ta.infinity-component.com/datasheet/9c-CYPD4126-40LQ...
[2] https://en.wikipedia.org/wiki/Apollo_Guidance_Computer#Other...