[dkz999]

>... the point where bacteria need to evolve so much to overcome new antibiotic approaches that they...

Can't. Changed it a bit for ya.

This is the zone we need to be in for any successful treatment. This is also why e.g. humans will never evolve bullet resistance.

[hedora]

Sure you can. This is what happened with Covid (though antibiotics had nothing to do with it). The early, more deadly strains are less fit for transmission to masked and (later) vaccinated populations, so we ended up with less virulent but more transmissible stuff like omicron.