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by ben_w 918 days ago
We start by doing them on mice (well, in vitro first, mice as the first in vivo), who have no say in the matter; and as mice are only rough analogues of humans, the human trials are still cautious once the animal trials are over.
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We also develop a lot of drugs with a which have side-effects, which will is probably better than no drugs in most cases, the side effects are because it's a lot of educated guesswork.