A good friend of mine was cured (knock on wood) of leukemia by CAR-T. She was one of the first people to get it during a clinical trial. She'd been through all the regular chemo, bone marrow transplant, etc as well as 3 other (failed) experimental treatments and was nearly beyond hope. It seems pretty certain that CAR-T saved her life. I went hiking with her not too long ago. Pretty amazing.
Anecdotal, but a former co-worker’s young daughter was just completely cleared of leukemia after several years of treatments that didn’t work followed by CAR-T