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by hedora 923 days ago
Any thoughts on these folks? (They are your direct competitor.)

https://probiorahealth.com/product/probiora/

A decade or so ago, their founder started with genetically modified bacteria that supposedly outcompete wildtype strains. The regulators responded in the only sane way possible, and it didn't go to human trials, from what I can tell.

List of publications from their founder:

https://pubmed.ncbi.nlm.nih.gov/?term=Hillman+JD&cauthor_id=...

Later, they just cultured a large number of wild strains, looking for ones with the desired properties, and now sell a mixture of three of them.

(Edit: I just realized the company in the article is selling the old work from Hillman's lab, but he is not a member of the team. I'm guessing you don't have a high opinion of this follow on work either then?)

2 comments

Your first link redirects to Google.

     curl -v https://probiorahealth.com/product/probiora/

    > GET /product/probiora/ HTTP/1.1
    > Host: probiorahealth.com
    > User-Agent: curl/8.1.2
    > Accept: */*
    > 
    < HTTP/1.1 302 Moved Temporarily
    < Server: nginx/1.14.0 (Ubuntu)
    < Date: ...
    < Content-Type: text/html
    < Content-Length: 170
    < Connection: keep-alive
    < Location: https://www.google.com
    < Strict-Transport-Security: max-age=63072000; includeSubDomains; preload
    < X-Frame-Options: SAMEORIGIN
    < X-Content-Type-Options: nosniff
    < X-XSS-Protection: 1; mode=block
    < Referrer-Policy: strict-origin
    < Permissions-Policy: geolocation=(),midi=(),sync-xhr=(),microphone=(),camera=(),magnetometer=(),gyroscope=(),fullscreen=(self),payment=()
Absolutely anecdotal - for a couple months Ive been taking a probioria tab every night before bed, and my mouth seems to be less gross pasty sticky in the morning.

I’m curious to see whether my dental hygienist notices any improvement next visit.