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Just discovered that google can convert long series of units. Say you wanted to do this, at the obvious risk of some undiscovered toxicity, and say you weigh 200lbs. At a cost of fullerene-c60 of $592 for 5 grams, at 1.7mg/kg, you're daily dose costs $18.26
http://www.google.com/?q=1.7mg%2Fkg+x+200lbs+x+592%2F5+dolla... Even worse, however, is the olive oil you have to eat each day, with the C60 disolved into it is 39 teaspoons!
http://www.google.com/?q=1.7+mg/kg+/+0.8+mg/ml+x+200+lbs+to+... Which is 4/5ths of a cup of oil per day. EDIT: I guess they didn't actually get a daily dose. we treated the rats daily only during 7 days and weekly
during the first two months, then every two weeks until
one control rat died.
Nor did they get dosed their entire lives, as earlier in the paper, we find that After five months of treatment (M15) one rat treated with
water only exhibited some palpable tumours in the
abdomen region. Due to the rapid development of tumours
(about 4 cm of diameter) this rat died at M17. As rats
are known to be sensitive to gavages, we decided to stop
the treatment for all rats and to observe their
behaviour and overall survival.
So, it looks like they only treated for 7 months, for the most part, once every two weeks, and then no further treatment. The treated rats, after only 7 months of treatment, achieved the benefit. |